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Cost

LillyDirect or a telehealth subscription: what each one actually costs

Buying straight from Lilly costs $299 to $699 a month depending on your dose, and that is the medication only. A telehealth provider charges you twice: a membership, and then the drug.

What that is based on

LifeMD is the clearest published example, at $39 for the first month and $149 a month after that for the membership, with medication explicitly not included, then $199 for a Wegovy pen or $299 for a Zepbound vial on top. So the honest comparison is not one price against another. It is Lilly direct plus finding your own prescriber, against a membership plus a drug price that comes with one. The trap in both is the same: the $299 you will have seen advertised is the 2.5 mg starting dose, and Lilly states it is not approved as a maintenance dose.

By John Weeks Updated August 25, 2026

Cash price · per month

$299 to $699

Lilly direct, by dose. A telehealth membership sits on top of a price like this one.

What it costs at each dose

What LillyDirect or a telehealth subscription: what each one actually costs costs at each dose, with the caveat on each figure.
Dose Per month Note
2.5 mg $299 Starting dose. Lilly states it is not approved as a maintenance dose
5 mg $399
7.5 mg $499 $449 on the purchase offer
10 mg $699 $449 on the purchase offer
12.5 mg $699 $449 on the purchase offer
15 mg $699 $449 on the purchase offer
  • 2.5 mg $299

    Starting dose. Lilly states it is not approved as a maintenance dose

  • 5 mg $399
  • 7.5 mg $499

    $449 on the purchase offer

  • 10 mg $699

    $449 on the purchase offer

  • 12.5 mg $699

    $449 on the purchase offer

  • 15 mg $699

    $449 on the purchase offer

Lilly self-pay for a one-month supply of the single-patient-use KwikPen, read from Lilly’s own terms on 25 August 2026. The purchase offer requires every refill to complete within 45 days of the previous delivery. Provider prices are listed separately and are not verified yet.

The short version

Lilly direct, starting dose
$299 a month at 2.5 mg
Lilly direct, maintenance doses
$399 to $699 a month
What Lilly direct does not include
A prescriber. You bring your own prescription
A worked example: LifeMD
Membership $39 the first month, then $149 a month, and it states medication is not included
LifeMD medication, charged separately
Wegovy pen from $199, Zepbound vial from $299 a month

Where you can actually get it

Three ways to buy the same medication, and they are not three versions of one price. Two of them charge you twice.

  • LillyDirect, straight from the manufacturer

    $299 to $699 a month

    $299 is the 2.5 mg starting dose. Lilly states it is not approved as a maintenance dose, so budget $399 to $699.

    Per month

    Care
    None
    Medication
    $399 to $699
    What that includes
    • The lowest published price for the medication itself
    • The single-patient-use KwikPen, direct from Lilly
    • No membership and no care subscription
    What it does not include
    • A prescriber. You bring a prescription you already hold
    • Labs, dose changes and ongoing review
    • Any help if a refill stalls
    See the price at every dose

  • Sesame, on Lilly’s own telehealth panel

    $99 a month for the care

    From $59 a month on annual prepay. Medication is charged separately and starts at $149 a month.

    Per month

    Care
    $99
    Medication
    not published

    Sesame publishes a floor across brand-name GLP-1s, from $149 a month, and no price for Zepbound specifically.

    What that includes
    • A prescriber, so you are not bringing your own prescription
    • Labs and ongoing review included in the care fee
    • Named on Lilly’s own list of independent telehealth companies
    What it does not include
    • The medication, which is a separate bill from $149 a month
    • Any guarantee of the LillyDirect price on the drug itself
    • A refund of the care fee if you stop

    Referral fee. It never changes what you pay, or the order of these routes. How we make money

    See Sesame pricing (opens in a new tab, we are paid a referral fee)

  • LifeMD, a telehealth subscription

    $149 a month for the membership

    $39 for the first month. LifeMD states medication is not included.

    Per month

    Care
    $149
    Medication
    $299
    What that includes
    • A prescriber and ongoing review
    • A published medication price, which most of this category does not show
    What it does not include
    • The medication. A Wegovy pen is from $199 and a Zepbound vial from $299 on top
    • The LillyDirect price. You are paying a membership as well
    Read our LifeMD audit

Referral fee from some of these. It never changes what you pay. How we make money

Providers offering this medication

  • LifeMD
    Medication $299/mo Zepbound vial Care $149/mo
  • Ro
    Medication $299/mo Zepbound KwikPen, against a $1,087 list price Care $74/mo
  • Hims & Hers
    Medication $299/mo Zepbound KwikPen or vial, medication only. Hims sells no Mounjaro Care $149/mo
  • Pallas Health
    Medication $299/mo Compounded, billed every 12 weeks after the first month
  • Sesame
    Care $99/mo Medication charged separately, not published
  • WeightWatchers
    Care $149/mo Medication charged separately, not published
  • Counsel Health
    Care $29/visit Medication charged separately, not published
  • General Medicine
    Care $30/visit Medication charged separately, not published
  • Form Health
    Care $299/mo Medication charged separately, not published
  • knownwell
    Care $299/visit Medication charged separately, not published
  • SkinnyRx
    First month $99 Compounded injectable, first month. No monthly rate published
  • MEDVi not checked
  • TrimRx
    Compounded $179 to $259 /mo
  • Mochi Health
    Care $79/mo Medication charged separately, not published
  • Noom
    Medication $149 /mo
  • Found
    All in $99 to $169 /mo
  • PlushCare
    Care $19.99/mo Care $129/visit Medication charged separately, not published
  • Alloy
    Medication $70 /mo Care $99/mo
  • Midi Health
    Care $250/visit Medication charged separately, not published
  • Maven Clinic not checked
  • Brello Health
    Compounded $79 to $247 /mo
  • Fella Health
    Medication $10/day Weight program. No monthly rate published
  • Zealthy
    Medication $151 /mo
  • Sprout Health
    Compounded $199 /mo
  • Direct Meds
    Compounded $249 to $297 /mo

More on Tirzepatide

Sources

Every claim above is checked against the primary text, and the date is the day we last opened it.

4 cited records
  1. 1
    Zepbound savings and self-pay pricing

    Eli Lilly and Company Primary text read and checked Checked August 25, 2026

  2. 2
    Wegovy cost, coverage and savings

    Novo Nordisk (NovoCare) Primary text read and checked Checked September 3, 2026

  3. 3
    LifeMD weight management: pricing and how it works

    LifeMD Primary text read and checked Checked September 3, 2026

  4. 4
    Online weight loss program

    Sesame Primary text read and checked Checked September 4, 2026